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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

A GLP-study according to ASTM method is available for propylene glycol methyl ether. This study is supported by a GLP-study equivalent to OECD guideline 201 and a non-GLP study according to DIN 38412.

Key value for chemical safety assessment

Additional information

In the key study, exposure concentrations ranged from 63 to 1,000 mg/l (nominal concentrations). A slight inhibition on cell count (7.1%) was observed after 7 days for all of the concentrations except for 500 mg/l. No significant inhibition was observed for biomass. Based on the nominal concentrations, the EC50 (biomass) was determined to be superior to 1,000 mg/l.

In the two supporting studies, concentrations ranging from 1 to 1,000 mg/l and from 31.25 to 500 mg/l were used. None of the concentrations tested caused more than 21% reduction in cell number compared to the mean cell number in the controls. Based on the nominal concentrations, the EC50 values were determined to be superior to 1,000 mg/l and 500 mg/l, respectively.

The 7 -day EC50 greater than 1000 mg/l will be taken into acount for the risk assessment.