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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

A GLP guideline study according to ASTM guideline is available for propylene glycol methyl ether. This study is supported by a non-GLP study according to EU method C.2 and a GLP-study equivalent to OECD guideline 202.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
23 300 mg/L

Additional information

In the key study daphnia were exposed to concentrations ranging from 1,412 to 50,000 mg/l. Based on these nominal concentrations, the 48-hour EC50 was determined to be 23,300 mg/l.

In the two supporting studies, daphnia were exposed to concentrations ranging from 62.5 to 500 mg/l and to 1,000 mg/l. Based on these nominal concentrations, the 48-hour EC50 were determined to be superior to 500 mg/l and superior to 1,000 mg/l, respectively, since no immobility was found during the test.

The 48-hour EC50 of 23,300 mg/l will be taken into account for the risk assessment.