(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Adequacy of study:

other information

Data source

Reference

Reference Type:

other: Body responsible for the test

Title:

Unnamed

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: 84/449/EWG, C.10 (Hydrolyse) "ENGLISH" (hydrolysis)

GLP compliance:

yes

Results and discussion

Dissipation DT50 of parent compound

Dissipation DT50 of parent compound 1

pH:

4

Temp.:

25 °C

DT50:

> 8 760 h

Dissipation DT50 of parent compound 2

pH:

7

Temp.:

30 °C

Hydrolysis rate constant:

s-1

DT50:

277 h

Dissipation DT50 of parent compound 3

pH:

7

Temp.:

25 °C

Hydrolysis rate constant:

s-1

DT50:

468 h

Dissipation DT50 of parent compound 4

pH:

9

Temp.:

30 °C

Hydrolysis rate constant:

s-1

DT50:

151 h

Dissipation DT50 of parent compound 5

pH:

9

Temp.:

25 °C

Hydrolysis rate constant:

s-1

DT50:

248 h