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EC number: 274-307-5 | CAS number: 70084-85-4 The complex residuum produced by the distillation of tallow fatty acids. It contains primarily glycerides, C16-20 saturated fatty acids, C36 dimer acid, C54 trimer acid and heavier polymeric acids.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No effects on fish up to the limit of water solubility
Key value for chemical safety assessment
Additional information
Studies are available for the pure homologue members of the fatty acid category. In addition some studies are summarized for certain fatty acid mixtures. Generally it could be stated that toxicity of fatty acids to aquatic organisms increases with increasing chain length up to the water solubility limit at a chain length of C12. For longer chains, no effects at saturation are observed.
For the fatty acids, hydrogenated tallow, distn. residues (CAS 700 -84 -4), which contains as main constituents C16 with a content of 5 - 35% and C18 with a content of 25 - 65%, read-across is performed to studies available for the pure homologues palmitic acid (C16 - CAS 57 -10 -3) and stearic acid (C18 - CAS 57 -11 -4). For evaluation of the mixture, only studies available for the pure homologues which were determined as key studies or used of a weight of evidence approach were chosen for a read-across. All linked studies conducted with the pure homologues were used in a weight of evidence approach to cover the endpoint "short-term toxicity to fish" for the considered fatty acid mixture.
Fatty acid homologue |
LC50 |
Water solubility* |
Test design and species |
Reference |
C16 - CAS 57-10-3 |
> 1000 mg/L (nominal) |
< 0.05 at 20 °C |
96 h, semi-static, |
Richterich and Mühlberg, 2001b |
C18 - CAS 57-11-4 |
> 10000 mg/L (nominal) |
insoluble |
48 h, static, |
Richterich and Mühlberg, 2001c |
* see category justification
The homologue C16 (palmitic acid: CAS 5 7 -10 -3) was tested on zebrafish (Danio rerio) according to ISO 7346 -1 in a semi-static test (Richterich and Mühlberg, 2001b). In the study nominal concentrations of 0.1, 0.5, 2.8, 16, 90, 250 and 1000 mg/L were tested. No mortality was observed at any test concentration and thus up to the limit of water solubility which is below 0.05 mg/L. In the study the LC50 was reported to be above 1000 mg/L.
The homologue C18 (stearic acid: CAS 57 -11 -4) was tested on golden orfe (Leuciscus idus) (Richterich and Mühlberg, 2001c). In the static test, which was conducted according to DIN 38412/15, the fish were exposed to different concentrations of the test substance (1000, 3000, 10000 mg/L nominal). In the study no effects on fish were reported, resulting in a LC50 > 10000 mg/L.
Concluding from the results reported for the pure homologues C16 and C18 no toxicity within the range of water solubility is expected for the considered fatty acid mixture.
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