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In accordance with column 2 of Annex IX, the study does not need to be conducted if the substance has a low potential for bioaccumulation. The log Kow of 1.1 for isobutyric acid (OXEA, 2009) indicates a low potential for bioaccumulation. Therefore and for reasons of animal welfare a fish study is not performed.

Based on an experimental log Kow of 1.1, the log BCF of isobutyric acid was estimated to be 0.5 (BCF = 3.162). In addition, a log BAF (upper trophic) of 0.31 (BAF = 2.06) was calculated using the method of Arnot-Gobas (ECT, 2010). The low BCF/BAF values indicate a low potential of isobutyric acid for bioaccumulation in aquatic and benthic organisms.



No data available (not required for REACH)