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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
The information does not come from a test report, and only minimum fields required can be filled in.

Data source

Reference
Reference Type:
other: database
Title:
Triethyl citrate, CAS# 77-93-0, RTECS# GE8050000
Author:
Canadian Centre for Occupational Health & Safety (CCOHS)
Year:
2010
Bibliographic source:
"Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63,p. 1892; cited in RTECS database (Registry of Toxic Effects of Chemical Substances, 2010)

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
peer-reviewed database
GLP compliance:
not specified
Remarks:
Peer-reviewed database, with no information on GLP status
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
Triethyl citrate
EC Number:
201-070-7
EC Name:
Triethyl citrate
Cas Number:
77-93-0
Molecular formula:
C12H20O7
IUPAC Name:
triethyl citrate

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
6 h
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
1 300 ppm
Based on:
not specified
Exp. duration:
6 h
Other findings:
Lungs, thorax or respiration:
- acute pulmonary oedema
- pleural effusion
- dyspnoea

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: other: EU-GHS
Conclusions:
LC50 (rat) = 1300 ppm/6h
Executive summary:

In the Registry of Toxic Effects of Chemical Substances (RTECS) database a LC50 (rat, inhalation) of 1300 ppm/6h is reported for triethyl citrate. No further details are available.