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EC number: 205-399-7 | CAS number: 140-11-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species, other
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 1982
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- This data was taken from the Handbook of Chemical Property Estimation Methods which describes the methods used for estimating bioconcentration factors in aquatic organisms. These methods are based on data from laboratory experiments that were designed to maintain relatively constant amounts of the chemical in the water environment, and where equilibrium concentrations of the chemical could be ascertained. This handbook is well recognised and reliable.
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- This data was taken from the Handbook of Chemical Property Estimation Methods which describes the methods used for estimating bioconcentration factors in aquatic organisms. These methods are based on data from laboratory experiments that were designed to maintain relatively constant amounts of the chemical in the water environment, and where equilibrium concentrations of the chemical could be ascertained.
- GLP compliance:
- no
- Remarks:
- Not required
- Radiolabelling:
- no
- Details on sampling:
- Not relevant
- Vehicle:
- no
- Details on preparation of test solutions, spiked fish food or sediment:
- Not relevant
- Test organisms (species):
- other: Please see below
- Details on test organisms:
- Calculations are based on the following species: Fathead minnow, Bluegill sunfish, Rainbow trout and Mosquito fish
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- not specified
- Hardness:
- Estimation by Calculation
- Test temperature:
- Estimation by Calculation
- pH:
- Estimation by Calculation
- Dissolved oxygen:
- Estimation by Calculation
- TOC:
- Estimation by Calculation
- Salinity:
- Estimation by Calculation
- Details on test conditions:
- Estimation by Calculation
- Nominal and measured concentrations:
- Estimation by Calculation
- Reference substance (positive control):
- not required
- Remarks:
- Estimation by Calculation
- Details on estimation of bioconcentration:
- BASIS FOR CALCULATION OF BCF
log Kow = 1.96 (Sangster, 1989)
Equation: Log BCF = 0.76 Log Kow - 0.23 (Equation no 5.2 - Handbook of Chemical Estimation Methods)
Applicable range of Kow = 7.9 to 8100000
Equation gives Log BCF = 8 - Type:
- BCF
- Value:
- 8 dimensionless
- Basis:
- not specified
- Details on kinetic parameters:
- Please see Table 1 for full calculation
- Metabolites:
- Not relevant
- Results with reference substance (positive control):
- Not relevant
- Details on results:
- Please see Table 1 for full calculation
- Reported statistics:
- Please see Table 1 for full calculation
- Validity criteria fulfilled:
- not applicable
- Remarks:
- Estimation by calculation
- Conclusions:
- The log Kow value of Benzyl acetate is 1.96 (Sangster, 1989). The logKow is below the trigger of 3 therefore the substance is not expected to bioaccumulate in living organisms.
- Executive summary:
The logKow value of Benzyl acetate was found to be 1.96 (Sangster, 1989). The logKow is below the trigger of 3 therefore the substance is not expected to bioaccumulate in living organisms. According to Column 2 of Annex IX of the REACH regulation, no bioaccumulation study is required if the logKow is below the trigger of 3.
However, data was taken from the Handbook of Chemical Property Estimation Methods which describes the methods used for estimating bioconcentration factors in aquatic organisms. These methods are based on data from laboratory experiments that were designed to maintain relatively constant amounts of the chemical in the water environment, and where equilibrium concentrations of the chemical could be ascertained.
Using the above logKow figure, a BCF was derived using the Handbook of Chemical Property Estimation Methods.The BCF was found to be 8. According to the guidance on information requirements and chemical safety assessment part B, Benzyl acetate is not considered to be hazardous as the BCF is below 10.
Reference
Table 1: results
Molecular Weight |
Log K(ow) |
Log (l/s) |
l/s (l/mol) |
S (mol/L) |
S (mg/L) |
Log BCF calc. |
BCF |
Bioaccumulation Significant? |
S measured mg/L |
Vp mmHg at 20°C |
VOC defined as vp >0.076 mm Hg |
HLC calc Pa m3/mol |
HLC Quoted/measured Pa m3/mol |
Ex Croner Env |
LogKoc calc |
Koc calc |
Koc quoted/measured |
Interpretation of Koc |
Log Koc calc |
Koc calc |
138 |
1.96 |
0.99 |
9.76 |
1.02E-01 |
14142 |
0.90 |
8 |
N |
2660 |
0.12 |
Y |
0.8 |
|
M |
1.39 |
25 |
250 (Tessenderlo) |
M |
1.8 |
57 |
Description of key information
The log Kow value of Benzyl acetate was found to be 1.96 (Sangster, 1989). The log Kow is below the trigger of 3 therefore the substance is not expected to bioaccumulate in living organisms. According to Column 2 of Annex IX of the REACH regulation, no bioaccumulation study is required if the log Kow is below the trigger of 3.
However, data was taken from the Handbook of Chemical Property Estimation Methods which describes the methods used for estimating bioconcentration factors in aquatic organisms. These methods are based on data from laboratory experiments that were designed to maintain relatively constant amounts of the chemical in the water environment, and where equilibrium concentrations of the chemical could be ascertained.
Using the above log Kow figure, a BCF was derived using the Handbook of Chemical Property Estimation Methods. The BCF was found to be 8. According to the guidance on information requirements and chemical safety assessment part B, Benzyl acetate is not considered to be hazardous as the BCF is below 10.
Key value for chemical safety assessment
- BCF (aquatic species):
- 8 dimensionless
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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