Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 222-429-4 | CAS number: 3468-63-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Algae:
The 72h-EC50 for growth rate inhibition (ERC50) and yield inhibition (EYC50) exceeded a
loading rate of 6.3 μg/L. The 72h-NOEC for both growth rate inhibition and yield inhibition was 6.3 μg/L.
Due to the very low solubility of Pigment Orange 5 in water, concentration levels that might be toxic for algae could not be reached.
Daphnia:
In the acute Daphnia study, C.I. Pigment Orange 5 showed no biologically significant effects at the saturated solution of the test item. Therefore, The EC50 (48h( was determined to be higher than the concentration of a saturated solution.
In the long-term Daphnia reproduction study, Pigment Orange 5 did not affect reproduction, growth and survival of Daphnia magna at the highest tested concentration of 6.3 µg/L after 21 days of exposure (NOEC).
Long term Fish:
NOEC (embryonic survival, post-hatch survival, body weight, body length) ≥ 6.3 μg/L, based on analytically confirmed nominal concentrations.
Additional information
No toxic effect was observed at the water solubility (6.3 μg/L) of the test substance at any of the aquatic toxicity tests.
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