Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study and GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes (incl. QA statement)
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl cyanoacetate
EC Number:
203-309-0
EC Name:
Ethyl cyanoacetate
Cas Number:
105-56-6
Molecular formula:
C5H7NO2
IUPAC Name:
ethyl 2-cyanoacetate
Constituent 2
Reference substance name:
[TN] ethyl cyanoacrylate [/TN][AM]>99%[/AM]
IUPAC Name:
[TN] ethyl cyanoacrylate [/TN][AM]>99%[/AM]

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.119
Temp.:
23 °C
pH:
6.1

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test item "Ethyl cyanoacetate is: log Pow = - 0.119