Registration Dossier
Registration Dossier
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EC number: 218-679-9 | CAS number: 2215-35-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In a key delayed contact hypersensitivity study, a group of albino guinea pigs was induced with 5% w/v test substance in mineral oil and then challenged with the same concentration (Costello, BA and Gilman, MR, 1982). All scores at the 24 hour and 48 hour challenge phase readings were zero. The test substance was not a sensitizer in the guinea pig.
In a supporting delayed contact hypersensitivity study, a group of 20 Dunkin-Hartley strain Guinea pigs was induced with 5% w/v test substance in mineral oil and then challenged with the same concentration (Costello, BA and Gilman, MR, 1982). All scores at the 24 hour and 48 hour challenge phase readings were zero. The test substance was not a sensitizer in the guinea pig.
Migrated from Short description of key information:
The substance is not skin-sensitizing to guinea gigs
Respiratory sensitisation
Endpoint conclusion
- Additional information:
no data available
Migrated from Short description of key information:
no data available
Justification for classification or non-classification
In accordance with EU CLP (Regulation (EC) No. 1272/2008), this substance does not meet the criteria for classification as a skin sensitizer.
No data are available for respiratory sensitization.
The substance is therefore not classifiable for this endpoint in accordance to the CLP Regulation (EC) No 1272/2008.
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