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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

ATMP and its salts are not readily biodegradable, based on 0 - 23% degradation in 28 days in reliable ready biodegradability studies.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

A reliable ready biodegradability study is available (OECD 301E, Douglas and Pell 1984), indicating 0% biodegradation in 28 days based on DOC removal.

A second reliable ready biodegradability study using pre-adapted inoculum (OECD 301D, Cremers and Hamwijk, 2006) indicated 22 -23% biodegradation in 28 days based on O2 consumption. (Note: This is a standard study with some acceptable deviations: pre-adapted inoculum was used and inorganic phosphate was omitted from the nutrient medium. In addition, solutions of test substance stock solution were made in natural seawater).

A reliability 2 SCAS test study is also available (Saeger et al. 1978). However, SCAS tests are generally considered less reliable than ready biodegradability tests. No statistically significant degradation was observed.

A reliable anaerobic biodegradability study (Zeneca Brixham Environmental Laboratory, 1995) indicated a biodegradation rate of 0 - 21% in 28d.

Furthermore, the results of three biodegradability in seawater studies (Drake, 2005, Rowlands, 2005 and Hamwijk and Cremers, 2005) (refer to Section 5.2.2) support the conclusion that the substance is not expected to be readily biodegradable.