Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Not reported
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Summary information only
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1970
Report date:
1970

Materials and methods

Principles of method if other than guideline:
Not reported
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Trisodium 2-(carboxylatomethyl(2-hydroxyethyl)amino)ethyliminodi(acetate)
EC Number:
205-381-9
EC Name:
Trisodium 2-(carboxylatomethyl(2-hydroxyethyl)amino)ethyliminodi(acetate)
Cas Number:
139-89-9
Molecular formula:
C10H18N2O7.3Na
IUPAC Name:
trisodium 2-({2-[bis(carboxymethyl)amino]ethyl}(2-hydroxyethyl)amino)acetate
Details on test material:
Not reported

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
Not reported

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Details on exposure:
Not reported
Doses:
Not reported
No. of animals per sex per dose:
Not reported
Control animals:
not specified
Details on study design:
Not reported
Statistics:
Not reported

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 330 other: mm^3
Based on:
not specified
Mortality:
Not reported
Clinical signs:
Symptoms: dyspnea, staggering, convulsions, diarrhea
Body weight:
Not reported
Gross pathology:
individual abdominal adhesions
Other findings:
Not reported

Any other information on results incl. tables

Not applicable

Applicant's summary and conclusion

Conclusions:
Trilon D fluseig was found to have an acute oral LD50 of about 330 mm^3 to mice exposed via intraperitoneal injection.
Executive summary:

Trilon D fluseig was found to have an acute oral LD50 of about 330 mm^3 to mice exposed via intraperitoneal injection.