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Adsorption/Desorption


The study does not need to be conducted because substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter.


Nevertheless, the estimation of the adsorption coefficient Koc of a read across substance had been applied according to the OECD Guideline 121


The poor solubility of the test item in water as well as in other solvents precluded the deduction of useful results. Using different sovent mixtures, partial dissolution of the test item had been possible. Elution from the HPLC-column, however, proved to be impossible in spite of different solvent systems used. Most probably, the test item had precipitated on the column. Therefore, Koc for the test item cannot be determined using the estimation method based on HPLC.

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