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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

A 96-hour LC50 value of 1.9 mg/l and NOEC of 1.3 mg/l have been determined for the effects of the test substance on Oncorhynchus mykiss.

Key value for chemical safety assessment

Additional information

Tetramethylsilane (TMS) is a highly volatile material with a very low boiling point. Due to the characteristics of the test substance and its behaviour in water, the study was conducted in a temperature-controlled room using a flow-through, closed system specifically designed for this testing in an attempt to minimize volatilization of tetramethylsilane during the 96-hour exposure.

The LC50 value was determined to be 1.9 mg a.i./L, using Spearman Karber estimates. Two data points (i.e., 100% mortality at 2.9 mg a.i./L and 0% mortality at 1.3 mg a.i./L) were used in determining the LC50 value. Due to the extremely steep dose response observed with this test substance, no data points with partial responses were generated. The No-Observed-Effect Concentration (NOEC) was determined to be 1.3 mg a.i./L.