Registration Dossier
Registration Dossier
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EC number: 231-749-3 | CAS number: 7719-12-2
Endpoint summary
Administrative data
Description of key information
Older proprietary studies of skin and eye irritation are available; additional published summary data are also available.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Skin irritation/corrosion
Phosphorus trichloride was found to cause corrosive effects in a skin irritation study (Imlay, 1977). Similar effects are reported in studies by Randall & Robinson (1990), Molodkina (1973) and Leist & Weigand (1978). A study summary (Pauluhn, 1984) reports corrosive effects within 60 second of the dermal application of 100 ul phosphorus trichloride.
Eye irritation
Severe reactions seen in an eye irritation study (Imlay, 1977) were confirmed in other studies by Randall & Robinson (1990), Molodkina (1973) and Leist & Weigand (1978).
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: highly irritating
Justification for classification or non-classification
Phosphorus trichloride is listed on Annex I of the Dangerous Substances Directive (67/548/EEC) with classification as 'Corrosive' (R35) 'Causes severe burns'. No change to this classification is proposed. Classification with (R41) 'Risk of serious damage to eyes' is implicit.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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