Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Summaries of the available fish, Daphnia and algal growth inhibition studies are presented below.

Rainbow trout were exposed to nominal exposure concentrations of 0, 10, 18, 32, 56 and 100 mg/L dipentaerythritol for 96 hours under semi-static conditions. Mean measured concentrations indicated that the test media had been adequately prepared and were within ± 20%, therefore the results of the study are based on nominal exposure concentrations. No mortality was observed in any of the test concentrations, therefore, the 96 hr LC50 was >100 mg/L. During the study 20% of the fish in the 100 mg/L treatment exhibited darkened pigmentation, therefore the no-observed effect concentration (NOEC) was observed to be 56 mg/L (Douglas & Bell, 1992).

Daphnia magna were exposed to a nominal exposure concentration of 0 and 100 mg/L dipentaerythritol for 48 hours under static conditions. The mean measured concentration of the 100 mg/L test treatment was 92 mg/L which indicated that the test medium had been adequately prepared. As the measured concentration was within ± 20% of the nominal concentration the results of the study are based on the nominal exposure concentration. No immobility was observed during the test therefore, the 48 hr EC50 was >100 mg/L, the corresponding no-observed effect concentration (NOEC) was observed to be 100 mg/L (Douglas & Bell, 1992).

The freshwater algae, Scenedesmus subspicatus, was exposed to a nominal exposure concentration of 100 mg/L dipentaerythritol for 72 hours under static conditions. The mean measured concentration of the 100 mg/L test treatment was 114 mg/L. As the measured concentration was within ± 20% of the nominal concentration the results of the study was based on the nominal exposure concentration. No effects were seen on either growth rate or biomass, therefore the 72 hour EbC50 and 72 hour ErC50 were both >100 mg/L, the corresponding no-observed effect concentration (NOEC) were both observed to be 100 mg/L (Douglas & Bell, 1992).

A summary of the available activated sludge study is presented below.

The toxicity of dipentaerythritol to activated sewage sludge was investigated in a respiration inhibition test according to OECD test guideline 209. Following three hours exposure to dipentaerythritol the EC50 was observed to be > 1000 mg/L (based on nominal exposure concentrations), the corresponding NOEC was observed to be 1000 mg/L (Hugill, 2015).

In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) no hazard was identified. Therefore according to REACH Annex I (5.0) exposure estimation is not necessary for long-term toxicity to fish or aquatic invertebrates. Consequently, in accordance with Column 2 of REACH Annex IX, long-term toxicity studies to fish and aquatic invertebrates do not need to be conducted as all identified uses of the substance are assessed as safe for the environment.