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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

The partition coefficient 1-octanol/water of isophorone diamine was determined according to OECD TG 107 (1995) and EC Method A.8 (1992) with the shake-flask method. The result was log Kow = 0.99 (Kow = 9.8) at 23 °C (pH 6.34 for water phase without test substance).

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
23 °C

Additional information

The GLP study with the shake-flask method is documented best. It characterizes the partially dissociated substance. The result from the other experimental study is in reasonable agreement. The QSAR results are somewhat higher, which reflects the fact that they characterize the undissociated substance:

log Kow = 0.79 (Hüls AG 1989,shake-flask) or 1.56 (CLOGP3) or 1.90 (Kowwin v.1.66).