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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Microorganisms were exposed to the analogue, o-sec-butylphenol, where the 3 hr EC50 was > 10 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
10 mg/L

Additional information

There are no reliable toxicity studies available for toxicity of o-tert-butylphenol to activated sludge microorganisms. However, reliable data are available for the analogue, o-sec-butylphenol and are included in the dossier.

Horton et al. (1991) conducted a reliable study on the toxicity of the analogue, o-sec-butylphenol, to activated sludge microorganisms following OECD 209 guidelines. Activated sludge microorganisms were exposed to the a control and 10 mg/L of the test substance for 3 hrs. Oxygen consumption was measured to determine the 3 hr EC50 of > 10 mg/L. Consequently, this value is taken to fullfil the toxicity to microorganisms endpoint.