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Toxicological information

Health surveillance data

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Administrative data

Endpoint:
health surveillance data
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given

Data source

Referenceopen allclose all

Reference Type:
other company data
Title:
Unnamed
Year:
1989
Reference Type:
publication
Title:
o-TOLUIDINE CAS No: 95-53-4 SIDS Initial Assessment Report.
Author:
OECD SIDS
Year:
2006
Bibliographic source:
UNEP Publications

Materials and methods

Study type:
health record from industry
Endpoint addressed:
acute toxicity: inhalation
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
o-toluidine
EC Number:
202-429-0
EC Name:
o-toluidine
Cas Number:
95-53-4
Molecular formula:
C7H9N
IUPAC Name:
o-toluidine

Results and discussion

Results:
During repair of machines a fitter was accidently exposed to o-toluidine (exposure route probably: inhalation, concentration not given). Treatment
with tolonium chloride reduced methemoglobinemia from 39,6 % to 2.6 %

Applicant's summary and conclusion