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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

A non-GLP study similar to OECD guideline 203 is available for valeric acid and a GLP-study according to OECD guideline 203 is available for a 
mixture of valeric acid and 2-methylbutyric acid. A third study with limited documentation is also provided.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
39 mg/L

Additional information

Three studies are available to assess the acute toxicity of valeric acid to fish. A non-GLP study conducted with pure valeric acid

and Pimephales promelas has been selected as the key study. The LC50 (96 hours) reported in this study is 39 mg/l. These data are supported by a GLP study conducted with a commercial mixture of valeric acid (ca. 64%) and 2 -methylbutyric acid (ca. 36%) and Rainbow Trout. The LC50 (96 hours) reported in this supporting study is 75.9 mg/l. A third, non-GLP study has also been included which was assigned a Klimisch score of 3 due to limited documentation. This study reported a short-term NOEC of 500 mg/L for the golden orfe exposed to pure valeric acid.