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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

No reliable acute toxicity data on fish are available for synthetic rutile. A read-across approach between synthetic rutile and TiO2 is used.  All reliable acute toxicity data to fish for TiO2 resulted in unbounded LC50 values ranging from >1 to >10000 mg TiO2/L, as observed for 4 different fish species in both freshwater and salt water. These reliable results cover a range of TiO2 products with varying particle size (from nano-particles to bulk powders).  All these results are taken together in a weight of evidence approach, and it is concluded that TiO2 is not acute toxic to fish at >1000 mg TiO2/L and at >10000 mg TiO2/L in freshwater and marine water, respectively.

Key value for chemical safety assessment

LC50 for freshwater fish:
1 000 mg/L
LC50 for marine water fish:
10 000 mg/L

Additional information