Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Description of key information

There are no oral, inhalation or dermal reproductive toxicity studies available for methylsilanetriyl triacetate. Data waivers are in place for this endpoint.

See attached data waiver justification and Section 5.6.3 of the Chemical Safety Report for further discussion.

Effect on fertility: via oral route
Endpoint conclusion:
no study available
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available

Effects on developmental toxicity

Description of key information

There are no oral, inhalation or dermal developmental toxicity studies available for methylsilanetriyl triacetate.

PLACEHOLDER: There is an ongoing pre-natal developmental toxicity study with methylsilanetriyl triacetate, conducted according to OECD TG 414 and in compliance with GLP, in line with ECHA final decision number TPE-D-2114426301-65-01/F.

Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available

Justification for classification or non-classification

The available data indicate that methylsilanetriyl triacetate does not need to be classified for toxicity to reproduction (fertility or developmental toxicity) according to Regulation (EC) No 1272/2008.

Additional information