Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

For the aquatic ecotoxicity endpoints a number of results have been read-across from Fatty acids, C12-18 and C18-unsatd., 2-sulfoethyl esters, sodium salts to coco fatty acids 2 -sulfoethyl sodium salt. Read-across from the source chemical Fatty acids, C12-18 and C18-unsatd., 2-sulfoethyl esters, sodium salts (CAS no 85408-62-4) to the target chemical coco fatty acids 2-sulfoethyl sodium salt is considered to be justified as both substances are very similar and the source chemical contains a higher content of longer alkyl chain products which are known to be more toxic than the shorter alkyl chain products. The conclusion that the source chemical is more toxic than the target chemical is considered sufficient to select the more toxic derivative as the worst-case representative in the hazard assessment of both substances. For this reason read-across of ecotoxicity results of the source chemical (C12-18 and C18-unsatd) to the target chemical (Coco) is considered to be justified without the introduction of an additional safety factor.

An overview of the most relevant results is provided in the table.

Method

Results

Results, converted to active ingredient

Remarks

Reference

 

 

 

 

 

Acute fish 96h

OECD 203

LC50 > 25 mg/L

LC50 > 9.9 mg/L (geomean)

Reliability 2

Unilever, 1982

Acute Daphnia 48h

OECD 202

EC50 > 50 mg/L

EC50 > 48 mg/L

Reliability 1

Read-across

Roberts, J 2008

Algae 72h

OECD 201

ErC50 > 4.8 mg/L

ErC50 > 4.8 mg/L

Reliability 1

Read-across

Roberts, J 2008

Activated sludge

OECD 209

EC50 = 1000 mg/L

EC50 = 687 mg/L

Reliability 2

Reinhardt, J

1994

 

 

 

 

 

Algae 72h

OECD 201

ErC10 = 0.31 mg/L

ErC10 = 0.3 mg/L

Reliability 1

Read-across

Roberts, J 2008

 

 

 

 

 

 

 

Conclusion

Acute toxicity results are available for three taxonomic groups (fish, invertebrates and algae). Solubility of fatty acid 2-sulfoethyl esters differs strongly with the alkyl chain length. The test substance has as for many other surfactants a specific Krafft point/cmc relation which means that at certain temperatures and concentrations cristallinic gels can be formed. 

Great effort has therefore being paid in preparing the test solutions and in quantifying the dissolved fraction of the different alkyl chain 2-sulfoethyl esters during the aquatic ecotoxicity tests. Most of the Key datapoint for the PNEC derivation is the algae study which is read-across from Fatty acids, C12-18 and C18-unsatd., 2-sulfoethyl esters, sodium salts to coco fatty acids 2 -sulfoethyl sodium salt. The coco fatty acid 2-sulfoethyl sodium salt contains a lower content of the more toxic but also less soluble longer alkyl chain 2-sulfoethylesters. Due to this lower solubility of the longer alkyl chain 2-sulfoethyl esters and evaluating the solubility data for each alkyl chain 2-sulfoethyl ester it is very likely that the fraction of the toxicity determining longer alkyl chains is almost equal for both substances when dissolved under the same conditions.