Di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide

Adsorption / desorption

Link to relevant study record(s)

Reference

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

21-November-2011 to 24-November-2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.

Qualifier:

according to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

HPLC estimation method

Media:

other: not applicable

Radiolabelling:

no

Test temperature:

30 °C

Details on study design: HPLC method:

HPLC-Conditions
Apparatus: Merck-Hitachi autosampler L-7200
Merck-Hitachi pump L-6200
Merck-Hitachi L-7400
Column: LiChrospher 100 CN, particle size 5 µm, 250 x 4.6 mm
HPLC Eluent: Water / methanol (45:55; v/v); pH 6.3
Detector type: refractive index
Temperature: Room temperature (21.1 °C)
Injection Volume: 20 µL
Flow: 1.0 mL/min
Retention Times: See Tables 4.3, 4.4 and 4.5

Analytical monitoring:

not required

Type:

Koc

Value:

52 600

Temp.:

30 °C

Remarks on result:

other: % Org Carbon not reported

Type:

log Koc

Value:

4.72

Temp.:

30 °C

Remarks on result:

other: % Org Carbon not reported

Details on results (HPLC method):

Standard Mean Retention Time (mins) Capacity Factor (k) Log10 k Log10 Km

Acetanilide 2.613 0.184 -0.734 1.25
Phenol 2.569 0.164 -0.784 1.32
Isoproturon 3.058 0.386 -0.413 1.86
Triadimenol 3.191 0.446 -0.350 2.40
Linuron 3.494 0.584 -0.234 2.59
Naphthalene 4.130 0.872 -5.93 x 10-2 2.75
Endosulfan-diol 3.488 0.581 -0.236 3.02
Fenthion 4.960 1.248 9.64 x 10-2 3.31
Phenanthrene 6.216 1.818 0.260 4.09
Diclofop-methyl 6.177 1.800 0.255 4.20
DDT 13.696 5.209 0.717 5.63

78-63-7 8.548 2.875 0.459 4.72

Formamide 2.206

Transformation products:

not measured

Validity criteria fulfilled:

yes

Conclusions:

The log of the adsorption coefficient (KOC) of di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide (CAS# 78-63-7) was calculated to be log KOC = 4.72 which is equal to a KOC value of 52600 using the HPLC method.

Executive summary:

The adsorption coefficient of the test item has been determined.

The determination was carried out using the HPLC screening method, designed to becompatible with Method 121 of the OECD Guidelines for Testing of Chemicals,22 January 2001. The log of the adsorption coefficient (KOC) of di-tert-butyl 1,1,4,4-tetramethyltetramethylene diperoxide (CAS# 78-63-7) was calculated to be log KOC = 4.72 which is equal to a KOC value of 52600 using the HPLC method.

Description of key information

The Koc of the substance was calculated as 52400 using OECD 121.

The Log Koc of the test substance was therefore approximately 4.72.

Key value for chemical safety assessment

Koc at 20 °C:

52 400

Additional information

The adsorption coefficient of the substance in soil and sludge using an HPLC method was estimated in a reliable GLP study following OECD 121. Based on two measurements of the substance, and by comparison with reference substances, the Koc of the substance was calculated as 52600 at 30°C.

The Log Koc of the test substance was therefore approximately 4.72.