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Toxicity to microorganisms

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Description of key information

Key value for chemical safety assessment

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Read across justification

Several criteria justify the use of the read across approach to fill data gaps for slack wax using other lubricant base oil analogs. Primarily the basis for the read-across is the similar physical chemical properties shared by the slack wax and other lubricant base oils.

In a key static 4-day Photobacterium phosphoreum luminescence inhibition study (KS=2) using other lubricant base oils as control substances, no significant luminescence inhibition was observed for Spindle oil (BP 320-400 ºC) and Neutral oil Ro NIII (BP 400-450 ºC), as well as for the n-paraffin dodecane. The NOEL for Spindle oil was > 1.93 mg/L and the NOEL for Neutral oil Ro NIII was > 2.17 mg/L (Riis et al., 1996).

This study is scientifically sound and satisfies the guideline requirement for toxicity to microorganisms.

Results of computer modelling to estimate aquatic toxicity show no acute toxicity of slack wax to aquatic microorganisms at or below its maximum attainable water solubility (Redman et al., 2010b). This supports the Riis et al. 1996 experimental results mentioned in the previous paragraph.