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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
no guideline available
Principles of method if other than guideline:
Principles of Menthode not stated in the report
GLP compliance:
not specified
Remarks:
(collection of data)
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Scenedesmus quadricauda
Test type:
static
Water media type:
not specified
Limit test:
no
Remarks on exposure duration:
no data
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
75 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate

compared with LT50 for bacteria

Validity criteria fulfilled:
not specified
Conclusions:
The effect on population growth is at 75 mg/l.
Executive summary:

The effect of benzonitrile on Scendedesmus quadricauda was assessed in a static laboratory study at pH 7.0 and T = 27 °C. The effect level based on population growth is 75 mg/l.

Description of key information

The effect of benzonitril on population growth of Scendedesmus quadricauda was determined to be at 75 mg/l.

Key value for chemical safety assessment

Additional information

The effect of benzonitrile on Scendedesmus quadricauda was assessed in a static laboratory study at pH 7.0 and T = 27 °C. The effect level based on population growth is 75 mg/l.

Further details are not reported in the secondary reference (Hazardous Materials. Benzonitrile) citing Bringmann & Kühn (Bringmann, G. and Kühn, R. 1977. Limiting values for the damaging action of water pollutants to bacteria (Pseudomonas putida) and green algae (Scendesmus quadricauda) in the ... Wasser Abwasser Forsch. 10 (3 -4): 87-98).

In other studies Bringmann & Kühn (not cited in this dossier) examined the influence of chemical substances on population growth of Scenedesmus quadricauda. In these studies the examined effect is the toxicity threshold (TT). The TT is determined using an analogous method of the cell multiplication test. The concentration at which the inhibitory action of a pollutant begins is present in that dilution from a series of dilutiuons of the test substance having, at the end of the test period, a mean extinction value that is >/= 3 % below the mean value of the extinction value for non-toxic dilutions of the test cultures.

Therefore, it is assumed that the described "effect on population growth" is equivalent to the TT value.