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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-06-20 to 200-11-28
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP and guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
thermal analysis
Melting / freezing pt.:
< -90 °C

 

 

Melting Point

Determination

Tei

Initial extrapoled temperature

Tp

Peak Temperature

Tef

Final extrapoled temperature

 

1

-42°C

-30°C

-18.6°C

 

2

-40.8°C

-27.2°C

-12.4°C

 

3

-39.4°C

-28°C

-11.8°C

 

4

-41.9°C

-29°C

-19.6°C

 

Mean

Standard deviation

-41.0°C

1.2°C

-28.6°C

 1.2°C

-15.6°C

  4.1°C

 

  

Despite the values obtained in the table above, the melting phase of the test item is not validated by DSC in the range -90 °C, +25 °C.

The non-reversible endothermal transition only visible during the first sweep in temperature cannot be validated as a melting point.

The temperature of -90 °C is not low enough to amorce the complete crystallisation: the beginning of the actual melting point is probably lower than - 90 °C.

If needed complementary analysis may be performed under cooling with liquid nitrogen, with a temperature range -150 °C, +25 °C.

Melting point

 T =   < - 90°C

Conclusions:
The melting point is <-90°C
Executive summary:

A GLP and guideline study is available. The range -90 °C, +25 °C was tested, and it appears that the temperature of -90 °C is not low enough to amorce the complete crystallisation; as a conclusion the actual melting point is lower than - 90 °C.

Description of key information

The melting point of the substance is <-90 °C.

Key value for chemical safety assessment

Additional information

A GLP and guideline study is available. The range -90 °C, +25 °C was tested, and it appears that the temperature of -90 °C is not low enough to amorce the complete crystallisation; as a conclusion the actual melting point is lower than - 90 °C.