Registration Dossier
Registration Dossier
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EC number: 231-211-8 | CAS number: 7447-40-7
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: data reported in brief
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku
- Author:
- Marhold JV
- Year:
- 1 972
- Bibliographic source:
- Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, 1972 ,p.8
- Reference Type:
- review article or handbook
- Title:
- Potasium chloride. toxicity profile
- Author:
- BIBRA
- Year:
- 1 989
- Bibliographic source:
- The British Industrial Biological Research|Association, Carshalton, UK
Materials and methods
- Principles of method if other than guideline:
- Single dermal application to the skin of rabbits
- GLP compliance:
- no
Test material
- Reference substance name:
- Potassium chloride
- EC Number:
- 231-211-8
- EC Name:
- Potassium chloride
- Cas Number:
- 7447-40-7
- Molecular formula:
- KCl
- IUPAC Name:
- potassium chloride
- Details on test material:
- no further data
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
- Duration of treatment / exposure:
- no data
- Observation period:
- no data
- Number of animals:
- no data
Results and discussion
In vivo
Results
- Irritation parameter:
- other: overall irritation
- Basis:
- mean
- Time point:
- other: no data
- Score:
- ca. 0
- Max. score:
- 6
- Reversibility:
- other: not adequate
- Remarks on result:
- other: the substance was evaluated to be not irritating to the skin of rabbits
- Irritant / corrosive response data:
- the substance was evaluated to be practically not irritating to the skin of rabbit
- Other effects:
- no data
Applicant's summary and conclusion
- Executive summary:
Potassium chloride was applied to the skin of rabbit and was evaluated as practically not irritating to the skin ( grade 0/6Marhold 1972).
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