Carbamic acid, N,N'-[1,3-phenylenebis[methyleneiminocarbonylimino(methyl-3,1-phenylene)]]bis-, di-C10-14-alkyl esters

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: "Particle Size Distribution, Fibre Length and Diameter Distribution" Guidance document, European Commission, ECB/TM/Feb 1996

GLP compliance:

yes (incl. QA statement)

Type of method:

Laser scattering/diffraction

Type of distribution:

volumetric distribution

Key result

Percentile:

D10

Mean:

ca. 7.82 µm

St. dev.:

0.157

Key result

Percentile:

D50

Mean:

ca. 33.23 µm

St. dev.:

0.395

Key result

Percentile:

D90

Mean:

ca. 66.82 µm

St. dev.:

1.178

Conclusions:

With a median mass diameter of about 33.23 µm, more than 98% of the particles were smaller than 100µm.

Executive summary:

The particle size distribution of the test item was performed according to the EC Guidance Document ECB/TM/February 1996 "Particle Size Distribution, Fibre Length and Diameter Distribution" using laser diffraction.

Water was used as solvent. Two solutions were prepared, both measured in duplicate.

With a median mass diameter of about 33.23 µm, more than 98% of the particles were smaller than 100µm.

Description of key information

D10: ca. 7.82 µm
D50: ca. 33.23 µm
D90: ca. 66.82 µm
Test item is produced and used in its dissolved form: there is no chance of inhalative exposure during entiry life cycle

Additional information

With a median mass diameter of about 33.23 µm, more than 98% of the particles were smaller than 100µm.