Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 236-671-3 | CAS number: 13463-41-7
Health surveillance data
Administrative data
- Endpoint:
- health surveillance data
- Type of information:
- other: letter from medical director
- Adequacy of study:
- weight of evidence
Data source
Materials and methods
- GLP compliance:
- no
Test material
- Reference substance name:
- Pyrithione zinc
- EC Number:
- 236-671-3
- EC Name:
- Pyrithione zinc
- Cas Number:
- 13463-41-7
- Molecular formula:
- C10H8N2O2S2Zn
- IUPAC Name:
- Bis [1-hydroxy-2(1H)-pyridinethionato-O,S](T-4)-zinc
Constituent 1
Method
- Type of population:
- occupational
- Details on study design:
- Population: ZPT manufacterurers
Dose: 0.35 mg/m3
Frequency: daily
Duration: 8 hours
Dose route: dermal and inhalation
Medical evaluations: every 1-2 years
Results and discussion
- Results:
- During 30 years of manufacturing experience with pyrithiones, no neurological abnormalities have been identified. Minor transient mucous membrane irritation has been noted.
Applicant's summary and conclusion
- Conclusions:
- Occupational contact with ZPT did not result in unacceptable adverse health effects. The information contained within this robust summary document comes from studies which are in the ownership of Arch Chemicals Inc. and which are protected in several regions globally. This information may not be used for any purpose other than in support of the Chemical safety Report submitted by Arch Chemicals Inc. under Regulation EC 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
