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Toxicity to microorganisms

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Description of key information

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
1 000 mg/L

Additional information

The acute toxicity of AZDN to micro-organisms has been assessed in an OECD 209 test. Based on measured inhibition rates, the 3-hour EC20and EC50could not be quantified because up to the highest nominal test concentration of 1000 mg/L less than 20% inhibition was noted after three hours incubation. A dose response at all test concentrations could not be observed. The maximum deviation in respiration rates was 19.1% at a concentration of 1000 mg 2,2’-Azobis[isobutyronitrile] (AZDN) per litre. Nevertheless, the 3-hour EC20and EC50are clearly higher than 1000 mg/L under the present test conditions.Even the test was not designed for a NOEC determination, the NOEC of 2,2’-Azobis[isobutyronitrile] (AZDN) may be established above 1000 mg/L.