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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

The 21 day-NOEC in a OECD 211 guideline study is ≥ 10 mg/l (nominal) for all mortality and the 21 day-EC10 is 2.5 mg/l (nominal) for reproduction.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
2.5 mg/L

Additional information

Chronic toxicity to invertebrates has been investigated in a reproduction test with Daphnia magna following the EU Method C.20 and OECD guideline 211 using semi-static exposure. No mortality was observed at the maximum concentration test (10 mg/l) and the NOEC reported as ≥ 10 mg/l (nominal) for mortality, however, for reproduction the 21 day EC10 value was reported as 2.5 mg/l (nominal). Exposure concentrations were verified by mean of HPLC-MSD and were ranging between 92.3 -100 per cent of the nominal values in the freshly prepared media and from 84.5 -100.9 per cent of nominal values in the media after 48 hours or 72 hours of exposure, respectively.