Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-825-9 | CAS number: 127-18-4
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
For freshwater algae the lowest toxicity values were the 72-h EC50 of 3.64 mg/l and the 72-h EC10 of 1.77 mg/l found in Chlamydomonas reinhardtii.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 3.64 mg/L
- EC10 or NOEC for freshwater algae:
- 1.77 mg/L
Additional information
A 72-h EC50 of 3.64 mg/l is reported for the algaeChlamydomonas reinhardtiiby Brack and Rottler (1994). The test conditions are fully described in the paper, and the test can be considered valid. In the same study Brack and Rottler (1994) reported a 72-h EC10 of 1.77 mg/l for the algaeChlamydomonas reinhardtii. For the marine speciesSkeletonema costatuma 7-day EC50 higher than 16 mg/l (Erickson and Freedman, 1978).
Other studies were not reliable or not assignable or did not assess effects on the growth rate. A 48-hour NOEC of 1 mg/l is reported by Erickson and Hawkins (1980) for estuarine phytoplankton. No indication is given as to the species tested and the endpoint assessed was photosynthesis therefore the result is not considered valid. Publication from the USEPA (1980) report a 96-hour EC50 of 500 mg/l (USEPA, 1980). Studies from Knie et al (1983) and Peason et al (1975) report effect on photosynthesis. These studies were not found critical and are not used in the assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
