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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Basic toxicokinetics

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Administrative data

basic toxicokinetics
Type of information:
other: theoretical approach
Adequacy of study:
key study
Study period:
28 May, 2010
other: not applicable
Rationale for reliability incl. deficiencies:
other: Study is based on expert judgement.

Data source

Reference Type:
study report
Report date:

Materials and methods

Objective of study:
other: toxicokinetic assessment
Principles of method if other than guideline:
A theoretical approach of the toxicokinetic properties of the substance based on the available physico-chemical properties and toxicological data.

Test material

Constituent 1
Reference substance name:
Reference substance 001
Details on test material:
- Name of test material (as cited in study report): Polyglycerol-3
- Substance type: organic liquid
- Physical state: Colourless to pale yellow viscous liquid
- Analytical purity:
27.9% Diglycerol
46.0% Triglycerol
17.9% Tetraglycerol
5.6% Pentaglycerol
2.6% Hexaglycerol and higher
- Purity test date: no data
- Lot/batch No.: RBA081008A
- Expiration date of the lot/batch: 31 May 2010
- Stability under test conditions: stabile

Results and discussion

Preliminary studies:
See below

Applicant's summary and conclusion

Interpretation of results (migrated information): low bioaccumulation potential based on study results
For risk assessment purposes the following absorption factors were derived:
oral absorption factor: 100%
dermal absorption factor: 100%
inhalation absorption factor: 100%