Registration Dossier

Administrative data

Description of key information

Skin irritation: Slightly irritating. Not classified
Eye irritation: Not irritating. Not classified.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

A skin irritation study was performed in accordance to OECD 404. Very slight erythema was noted at two treated skin sites 24 h after patch removal. One treated skin site appeared normal throughout the study and the remaining two treated skin sites appeared normal at the 48 hour observation. 

An eye Irritation study was performed in accordance to OECD 405. No corneal or iridial effects were noted during the study. Minimal conjunctival irritation was noted in all treated eyes one hour after treatment. All treated eyes appeared normal at the 24-hour observation. 

Justification for classification or non-classification

The findings from testing do not warrant classification for skin or eye irritation.