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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

A number of non-guideline studies performed with sodium fluoride are available.  EC50 values for marine invertebrates range from 10.5-39 mg/L.  EC50 values for daphnids range from 97-352 mg/L; benthic insect larvae were found to be more sensitive, with EC50 values of 26-48 mg/L (test with soft water).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
26 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
10.5 mg/L

Additional information

Camargo & Tarazona (1991) report that benthic larvae are sensitive to the concentration of fluoride, with EC50 values ranging from 26 -48 mg/L (actual concentration); however the study was performed in soft water. The EU RAR reviews and summarises the available data on short-term toxicity to aquatic invertebrates. The reported EC50 values for Daphnia sp. range from 97-352 mg/L and are based on nominal concentrations; EC50 values of 10.5 -39 mg/L are reported for marine invertebrates. The ICD summarises the available data on the short-term toxicity of sodium fluoride to aquatic invertebrates and reports EC50 values of 109 -340 mg/L; EC50 values of 30 -500 mg/L are reported for marine invertebrates.