Registration Dossier

Administrative data

Endpoint:
bioaccumulation in sediment species: invertebrate
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion

Conclusions:
Based on physico-chemical parameters, the substance is highly unlikely to bioaccumulate.
Executive summary:

In accordance with Column 2 of REACH Annex IX, Section 9.3.2. this study need not be conducted if the substance has a low potential for bioaccumulation (for instance a log Kow < 3) and/or a low potential to cross biological membranes. The substance has been demonstrated to have a partition coefficient value of >-6.2, an extremely low fat solubility, a high level of hydrophilicity plus is of a relatively large molecular size, indication that it is unlikely to cross biological membranes.

 

As such, it is deemed inappropriate to test the substance for this endpoint, both on scientific and animal welfare grounds.