Registration Dossier

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not translated (Russian), only abstract in English

Data source

Reference
Reference Type:
publication
Title:
Camplex assessment of the state of an olfactory analyzer in odor-exposed white rats
Author:
Kostrodymov NN et al.
Year:
1987
Bibliographic source:
Gig. Sanit. 12, 79 - 80

Materials and methods

Principles of method if other than guideline:
acute inhalation toxicity
GLP compliance:
not specified
Test type:
standard acute method
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
other: no data
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
4 h
Concentrations:
0.4 mg/l
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LC0
Effect level:
0.4 mg/L air
Exp. duration:
4 h

Applicant's summary and conclusion