Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-375-0 | CAS number: 106-22-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature available
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
- Report date:
- 1973
- Reference Type:
- secondary source
- Title:
- Fragrance Raw Materials
- Author:
- Opdyke DLJ
- Year:
- 1 975
- Bibliographic source:
- Food Cosmet. Toxicol. 13, 757 - 758
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- Moreno OM
- Year:
- 2 001
- Bibliographic source:
- RTECS: Update 199701, (2000/01)
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 2 006
- Reference Type:
- secondary source
- Title:
- ALIPHATIC BRANCHED-CHAIN SATURATED AND UNSATURATED ALCOHOLS, ALDEHYDES, ACIDS, AND RELATED ESTERS
- Author:
- Pronk IMEJ
- Year:
- 2 007
- Bibliographic source:
- First draft; WHO Info
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Method: other: acute oral toxicity
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Citronellol
- EC Number:
- 203-375-0
- EC Name:
- Citronellol
- Cas Number:
- 106-22-9
- Molecular formula:
- C10H20O
- IUPAC Name:
- 3,7-dimethyloct-6-en-1-ol
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Doses:
- 2025, 2560, 3200, 4000, 5000 mg/kg bw
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 3 450 mg/kg bw
- 95% CL:
- 3 210 - 3 690
- Mortality:
- 5000 mg/kg bw: 8/10
4000 mg/kg bw: 6/10
3200 mg/kg bw: 7/10
2560 mg/kg bw: 0/10
2050 mg/kg bw: 1/10
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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