Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study meets generally accepted scientific principles, acceptable for assessment as supporting data

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Principles of method if other than guideline:
pH-measurements taken in the laboratory for solutions of 96% pure, DTPTMP with increasing stoichometric amounts of the corresponding base (NaOH).
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
[[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid
EC Number:
239-931-4
EC Name:
[[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid
Cas Number:
15827-60-8
Molecular formula:
C9H28N3O15P5
IUPAC Name:
[[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid
Test material form:
solid

Results and discussion

pH valueopen allclose all
pH value:
2.3
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP
pH value:
2.5
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-1Na
pH value:
2.8
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-2Na
pH value:
4
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-3Na
pH value:
5.6
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-4Na
pH value:
6.7
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-5Na
pH value:
7.7
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-6Na
pH value:
9
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-7Na
pH value:
10.5
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-8Na
pH value:
11.2
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-9Na
pH value:
11.4
Temp.:
20 °C
Concentration:
2 other: mmol/l
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-10Na

Any other information on results incl. tables

Table 1: Titration in water

Determination 1

Sample mass (mg) 171.9

Equivalent NaOH

0

1

2

3

4

5

6

7

8

9

10

1N NaOH (ml)

0.000

0.287

0.574

0.861

1.147

1.434

1.721

2.008

23.295

2.582

2.869

pH

2.29

2.49

2.83

4.04

5.59

6.69

7.72

9.06

10.51

11.18

11.42

 

Determination 2

Sample mass (mg) 170.9

 

Equivalent NaOH

0

1

2

3

4

5

6

7

8

9

10

1N NaOH (ml)

0.000

0.285

0.570

0.856

1.141

1.426

1.711

1.996

2.282

2.567

2.852

pH

2.28

2.48

2.82

4.02

5.57

6.67

7.74

9.03

10.47

11.15

11.38

 

 

Applicant's summary and conclusion

Conclusions:
The pH of the substance has been determined using an acceptable scientific method. The result is considered reliable.