Registration Dossier
Registration Dossier
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EC number: 212-081-1 | CAS number: 760-67-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound 2 -ethylhexanoyl chloride: Acutely harmful to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Remarks:
- Parent compound: 2 -ethylhexanoyl chloride
- Effect concentration:
- 66.3 mg/L
Additional information
Parent compound: 2 -ethylhexanoyl chloride
The acute toxicity on fish was studied according to OECD 203 with Danio rerio under static conditions (BASF AG, 1998). The test item hydrolyses rapidly and forms 2-ethylhexanoic acid (CAS 149-57-5) and hydrochloric acid (HCl, CAS 7647 -01 -0). Therefore, the analytical verification of the test item concentrations was based on the hydrolysis product 2 -ethylhexanoic acid. The test item concentrations were initially in the range of 63.8% to 94.8% and after about 96 h between 43% and 86.2%. All fish died at the two highest test item concentration during the first day (nominal: 464 and 1000 mg/L; 1000 mg/L, pH-adjusted). Mortality occurred also in the two lower test item concentrations (nominal: 100 and 215 mg/L). The LC50 was calculated based on the mean measured concentrations: 96 -h LC50 = 66.3 mg/L. In conclusion, valeric acid is considered to be acutely harmful to fish.
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