Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Endpoint:
partition coefficient
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The review reports the octanol/water partition coefficient of benzylchloride obtained via QSAR or with an experiment. Very few data are giving concerning methodology and results. However, this study should be considered as reliale with restrictions, a Klimisch 2g: data from collection of peer-reviewed data.
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
review article or handbook
Title:
Exploring QSAR. Hydrophobic, electronic, and steric constants
Author:
Hansch C., Leo A. and Hoekman D.
Year:
1995
Bibliographic source:
ACS Professional Reference Book, American Chamical Society, Washington, DC

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): A-chlorotoluene

No more data available

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.3
Temp.:
20 °C
pH:
7
Remarks on result:
other: Information on temperature and pH was not available in the article.

Any other information on results incl. tables

The value reported is the preferred value measured as or converted to the neutral form

No more data available

Applicant's summary and conclusion

Conclusions:
This review reports an octanol/water partition coefficient of 2.30 log Pow for benzylchloride.
Executive summary:

This review reports the octanol/water partition coefficient of benzylchloride (CAS n° 100 -44-7) to be 2.30 log Pow. No further information is available on the methodology followed.

The study is however considered as reliable with restrictions since the data is obtained from a collection of peer-reviewed data and since this publication is quoted as a reliable with restrictions source of data for octanol/water partition coefficient data in the ECHA guidance on specific endpoint information requirement R7.a.