Registration Dossier
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EC number: 206-156-8 | CAS number: 304-59-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 8 - 22 July 1994
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Official and peer reviewed source. Published by the Japanese Official Bulletin of the Ministry of International Trade and Industry (former MITI) and currentl accesible via de biodegradation database of the Japanese National Institute of Technology and Evaluation.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Disodium tartrate
- EC Number:
- 212-773-3
- EC Name:
- Disodium tartrate
- Cas Number:
- 868-18-8
- Molecular formula:
- C4H6O6.2Na
- IUPAC Name:
- disodium tartarate
- Details on test material:
- Anhydrous disodium tartate used as test substance (CAS: 868-18-8). Referred to as K-1129 in the report, with a mol wt of 194.05 and a reported purity of 99.8%. Batch tested reported as M3R8322. Original report available only in Japanese.
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Concentration of activated sludge: 30 mg/L Cultivation conditions reported as regular. Aerobic conditions maintaine in a closed system.
Innoculum obtained from 10 samples obtained from waste water treatment plants in: Fushiko River plant (Sapporo-shi, Hokkaido), Nakahama plant (Osaka-shi, Osaka), Kitakami River (Ishinomaki-shi, Miyagi), Yoshinogawa (Tokushima-shi, Tokushima), Gulf of Hiroshima (Hiroshima-shi, Hiroshima), Fukashiba plant (Fashima-gun, Ibaraki), Ochiai plant (Shinjuku-ku, Tokyo), The Shinano River (Nishikanbara-gun, Niigata), Lake Biwa-ko (Ootsu-shi, Shiga), Gulf of sinus Sea (Kitakyuushuu-shi, Fukuoka).
Inoculum mixed and prefiltered. Glucose / peptone medium used for cultivation. Dissoolved oxygen, pH and temperature of sludge culture is measured during culture and subjected to microscoic examination for abnormalities. None were detected. - Duration of test (contact time):
- 14 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimationopen allclose all
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter followed for biodegradation estimation:
- TOC removal
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Remarks:
- HPLC
- Details on study design:
- Test substance concentration = 100 mg/L. Test performed in triplicate test vessels at a temperature of 25 ±1 C°.
Water + test substance as well as a control blank were included in the experimental design. Test substance reported as stable under storage conditions.
Reference substance
- Reference substance:
- aniline
- Remarks:
- Batch number 2823. Reagent grade. Manufactured by Showa chemicals.
Results and discussion
- Test performance:
- Degradation of reference substance, expressed in terms of BOD was 63% at day 7 and 73% at day 14. Therefore test conditions are considered acceptable.
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 75
- St. dev.:
- 4.73
- Sampling time:
- 14 d
- Parameter:
- % degradation (TOC removal)
- Value:
- 92
- St. dev.:
- 1
- Sampling time:
- 14 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 100
- St. dev.:
- 0
- Sampling time:
- 14 d
BOD5 / COD results
- Results with reference substance:
- Degradation of reference substance, expressed in terms of BOD was 63% at day 7 and 73% at day 14. Therefore test conditions are considered acceptable.
Any other information on results incl. tables
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- Degradation of reference substance, expressed in terms of BOD was 63% at day 7 and 73% at day 14. Therefore test conditions are considered acceptable.
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Biodegradation at 14 d expressed in terms of BOD with respecto to ThOD is >60%. Thereby according to criteria for OECD method 301C, the substance is considered to be readily biodegradable.
- Executive summary:
Report on test performed in 1994 under Chemicals Programme sponsored by Japanese Ministry of International Trade and Industry (MITI) according to OECD Guideline 301C and under GLP indicates that analogue sodium ditartrate is readily biodegradable under specified test conditions after 14d. Biodegradability was estimated according to three parameters: BOD reduction, TOC reduction and test substance reduction as estimated by HPLC. The minimum average % biodegradation (mean of three replicates) obtained was of 75% in terms of BOD and of 100% as determined by substance disappearance estimated by HPLC analysis. Thereby, as predicted from its molecular structure disodium tartrate is considered to be readily biodegradable, as > 60% biodegradation is obtained in the MITI test. This analogue is considered to be a suitable predictor of the biodegradability of Potassium Sodium Tartrate, as the organic group of the submission substance is identical, being the only difference the exchange of one sodium atom for a potassium atom, which is irrelevant in terms of the degradable organic portion of the molecule.
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