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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
other: Observations at occupational exposure
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Short summary, no methodological details available. All information on this study, including the reliability grade, is derived from OECD SIDS 3-hydroxy-2-naphthoic acid CAS: 92-70-6 dated 2004-11-23, as the complete study report is not at hand. A report number has not been stated for this study by the OECD SIDS (1994).

Data source

Reference
Reference Type:
secondary source
Title:
OECD SIDS 3-Hydroxy-2-naphthoic acid CAS: 92-70-6
Author:
OECD
Year:
2004
Bibliographic source:
OECD SIDS 3-Hydroxy-2-naphthoic acid CAS: 92-70-6, UNEP Publications 2004: 1-72, Ref. 48
Report date:
2004

Materials and methods

Study type:
not specified
Endpoint addressed:
skin irritation / corrosion

Test material

Constituent 1
Chemical structure
Reference substance name:
3-hydroxy-2-naphthoic acid
EC Number:
202-180-8
EC Name:
3-hydroxy-2-naphthoic acid
Cas Number:
92-70-6
Molecular formula:
C11H8O3
IUPAC Name:
3-hydroxynaphthalene-2-carboxylic acid

Method

Type of population:
occupational
Reason of exposure:
other: occupational, but not specified if intended or not
Exposure assessment:
not specified

Results and discussion

Clinical signs:
No relevant clinical signs at exposure levels < 1 mg/m3. At higher exposures, skin and mucosal irritation have been reported, beginning with itching of the skin.

Applicant's summary and conclusion

Conclusions:
No relevant occupational health effects have been evident for workplaces at exposure levels below 1 mg/m3. At higher
exposures, skin and mucosal irritation have been reported, beginning with itching of the skin.
Executive summary:

In humans, no relevant occupational health effects have been evident for workplaces at exposure levels below 1 mg/m3. At higher exposures, skin and mucosal irritation have been reported, beginning with itching of the skin.