Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 204-468-9 | CAS number: 121-43-7
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Study period:
- No data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Meets generally accepted scientific standards with acceptable restrictions.
Data source
Reference
- Reference Type:
- publication
- Title:
- Occupational contact dermatitis from alkanolamine borates in metalworking fluids.
- Author:
- Bruze, M, Hradil, E, Erikson I-L, Gruvberger B and Widstrom
- Year:
- 1 995
- Bibliographic source:
- Contact Dermatitis 32: 24 - 27.
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- other: Three patients; no other data.
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: No data
- Deviations:
- not specified
- Principles of method if other than guideline:
- Three patients were patch tested. Case No 1: Al-test, Astra Agency, Sweden with 25 µL of test agent. Case 2 & 3 ; Finn Chamber, Epicon OY, Finland with 15 µL of test agent.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Borates
- IUPAC Name:
- Borates
- Details on test material:
- - Name of test material: Boric acid tested at 3 % w/v.
Constituent 1
Method
- Type of population:
- not specified
- Controls:
- No data
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- Not sensitising.
Applicant's summary and conclusion
- Conclusions:
- Boric acid tested at 3 % w/v in water showed no sensitisation in a patch test on three patients.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
