Registration Dossier
Registration Dossier
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EC number: 202-640-8 | CAS number: 98-13-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1969
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: The study did not meet current guideline requirements for skin irritation/corrosion. The original report was not available for review.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 969
- Reference Type:
- other company data
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- No data available.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Trichloro(phenyl)silane
- EC Number:
- 202-640-8
- EC Name:
- Trichloro(phenyl)silane
- Cas Number:
- 98-13-5
- Molecular formula:
- C6H5Cl3Si
- IUPAC Name:
- trichloro(phenyl)silane
- Details on test material:
- No data.
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
- Duration of treatment / exposure:
- No data.
- Observation period:
- No data.
- Number of animals:
- No data.
Results and discussion
In vivo
- Other effects:
- Highly corrosive. Causes severe burns.
Applicant's summary and conclusion
- Interpretation of results:
- highly corrosive
- Remarks:
- Migrated information Criteria used for interpretation of results: not specified
- Conclusions:
- The test substance was determined to be highly corrosive in a study which did not meet current guideline requirements for acute dermal toxicity. It does, however, add weight of evidence for trichloro(phenyl)silane toxicity.
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