Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1951
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: The study did not meet current guideline requirements for acute oral toxicity. It does however add weight of evidence for trichloro(phenyl)silane toxicity.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1951
Report date:
1951

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Not enough information available to specify.
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Trichloro(phenyl)silane
EC Number:
202-640-8
EC Name:
Trichloro(phenyl)silane
Cas Number:
98-13-5
Molecular formula:
C6H5Cl3Si
IUPAC Name:
trichloro(phenyl)silane
Details on test material:
No data.

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
No data.
No. of animals per sex per dose:
No data.
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 400 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The LD50 value of 2.4 g/kg was determined in a study which did not meet current guideline requirements for acute oral toxicity. It does, however, add weight of evidence for trichloro(phenyl)silane toxicity.