Registration Dossier
Registration Dossier
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EC number: 225-464-3 | CAS number: 4861-19-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Urea showed a low toxicity in Daphnia magna with a 24 hr EC50 of >10000 mg/L. Phosphoric acid demonstrated an 48 hr EC50 of >100 mg/L with a NOEC of 56 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Urea phosphate will dissociate directly into urea and phosphoric acid in aqueous environment.
The 24 hour EC50 for urea in Daphnia was reported to be >10000 mg/L; urea is not acutely toxic to daphnids.
For phosphoric acid a study was performed according to OECD TG 202 and EC Method C.2, and according to GLP principles. In the study, Daphnia magna were exposed to aqueous solutions of phosphoric acid under static test conditions.The pH was adjusted to 7 (pH from 7 to 7.8). The concentrations that were tested were 10, 18, 32, 56 and 100 mg/L. The 48h-EC50 was >100 mg/L and the NOEC = 56 mg/L, based on nominal concentrations. Measured test concentrations ranged from 82% to 94% of nominal at the start of the test, and from 80 % to 92% after 48h.
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