Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

No data are available for Chlorodimethylsilane. A 96-hour LC50 of 271 mg/L has however been determined for the effects of a read-across substance, Trimethylsilanol (CAS 1066-40-6), on mortality of Oncorhynchus mykiss.  A NOEC of 128 mg/L has been determined in the same test. A 96-hour LC50 value of >126 mg/L and NOEC of ≥126 mg/L have been determined for the effects of a second read-across substance, Dimethylsilanediol, 1066-42-8, on mortality of O. mykiss. The results of the test with Trimethylsilanol (CAS 1066-40-6) have been selected as the key results because they are definitive values.

Key value for chemical safety assessment

Additional information

No test data for short-term toxicity to fish are available for Chlorodimethylsilane. However reliable data for short-term toxicity to fish are available for the related substances Dimethylsilanediol, 1066-42-8, and Trimethylsilanol, 1066-40-6. The hydrolysis half-life of Chlorodimethylsilane indicates that, under conditions relevant to the acute fish toxicity test, hydrolysis to Dimethylsilanol and hydrogen chloride will occur. The properties of hydrogen chloride are well characterised and are discussed in the CSR. Its effects on aquatic organisms are limited to those that result from changes to pH in unbuffered media. Read-across from trimethylsilanol and dimethylsilanediol to dimethylsilanol is appropriate because all are small molecule alkylsilanols containing Me-Si and HO-Si groups; their properties are expected to be similar.