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Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

Administrative data

Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: chemical properties

Test material

Constituent 1
Reference substance name:
Fatty acids C16-18, sodium salt
IUPAC Name:
Fatty acids C16-18, sodium salt
Constituent 2
Reference substance name:
Fatty acids, C16-18, sodium salts
EC Number:
270-299-2
EC Name:
Fatty acids, C16-18, sodium salts
Cas Number:
68424-38-4
Molecular formula:
Unspecified
IUPAC Name:
Fatty acids, C16-18, sodium salts

Results and discussion

Test substance stable:
yes
Transformation products:
not measured

Any other information on results incl. tables

Due to the chemical structure of fatty acid C16 -18 sodium salt (ionic structure), the test item can be considered to be practicability insoluble in organic solvents. Thus, stability in organic solvents cannot be determinded.

Moreover, the behaviour of fatty acid C16 -18 sodium salt in aqueous solution was investigated in the course of the study 10 -15551-2 "Hydrolysis as a function of pH according to OECD guideline for the testing of chemicals 111".

It was shown that the predominant reaction of fatty acid C16 -18 sodium salt in the presence of protonic solvents (water, but also applicable to organic solvents like methanol or ethanol) is the protonation of the carboxylic moiety to form the free fatty acids. No further reaction of the free acids was observed, although being extracted with diethyl ether, then evaporated and resolved in acetonitril (see study report 10 -15551 -2).

Fatty acid C16 -18 sodium salt and free C16 -18 fatty acids are considered to be stable in organic solvents due their chemical properties.

Applicant's summary and conclusion

Conclusions:
Due to the chemical structure of fatty acid C16 -18 sodium salt (ionic structure), the test item can be considered to be practicability insoluble in organic solvents. Thus, stability in organic solvents cannot be determinded.

Moreover, the behaviour of fatty acid C16 -18 sodium salt in aqueous solution was investigated in the course of the study 10 -15551-2 "Hydrolysis as a function of pH according to OECD guideline for the testing of chemicals 111".

It was shown that the predominant reaction of fatty acid C16 -18 sodium salt in the presence of protonic solvents (water, but also applicable to organic solvents like methanol or ethanol) is the protonation of the carboxylic moiety to form the free fatty acids. No further reaction of the free acids was observed, although being extracted with diethyl ether, then evaporated and resolved in acetonitril (see study report 10 -15551 -2).

Fatty acid C16 -18 sodium salt and free C16 -18 fatty acids are considered to be stable in organic solvents due their chemical properties.